The Communiqué No: IEG-2005 / 3 issued by the Ministry of Health on the Analysis Methods Required for the Control of Cosmetic Product Compositions sets out the principles for the analysis methods for the determination of total fluoride in toothpastes as well as many chemical substances listed.

According to the aforementioned communiqué, the determination of total fluoride in toothpastes is performed according to Method VIII in the annex.

Method VIII - Determination of Total Fluoride in Toothpastes was found suitable for the determination of total fluoride in toothpastes. This method is suitable for amounts not greater than 0,25 percent.

Fluoride is still a controversial substance. In the early days, it was used freely in toothpaste making because low doses prevented tooth decay. However, nowadays, the benefits of fluoride are discussed more than this benefit. The most important feature of fluoride is that it is among the chemicals that accumulate in the human body. Fluoride, which cannot be removed from the body, accumulates mostly in the bones and brain.

The amount of fluoride that can be used in oral care products and toothpastes is limited according to the Cosmetic Regulation. Accordingly, the total fluoride concentration should not exceed 0,15 percent. The same is true in the Cosmetic Directive 1223 / 2009 / EC published by the European Union. This limit has been considered safe for human health. Among the priorities of the cosmetic product sector, consumer safety is the first priority. As with all other cluster chemicals, fluoride is harmful if it enters the human body above a certain rate. However, it is still one of the most important active ingredients in the prevention of dental caries.

Both legal regulations and standards published by domestic and foreign organizations impose some limitations and the authorized laboratories comply with these limitations in the analysis of fluoride determination performed within the scope of physical and chemical analyzes.

Laboratories must also be accredited in accordance with the TS EN ISO / IEC 17025 General Requirements for the Competence of Testing and Calibration Laboratories.