Multiple mycotoxin analysis (LC-MS / MS)

Multiple Mycotoxin Analysis (LC-MS / MS)
Multiple Mycotoxin Analysis (LC-MS / MS)

 

Mycotoxins, which cause high poisoning in humans and animals, can occur in all stages of the food industry and in post-production storage and transportation activities. This has sometimes very critical consequences for food safety and human health.

Among the mycotoxins produced by various fungal species, the most noteworthy are:

  • Aflatoxins (AFT)
  • Deoxynivalenol (DON)
  • Fumonisins (fumonisin B1)
  • Ochratoxin A (OTA) and Ochratoxin B
  • patulin
  • Trichothecenes (T-2 toxin)
  • Zearalenone (ZON)

Many of the known mycotoxins are strong in heat treatment and chemical stability. In this regard, mycotoxins can be partially removed from foodstuffs by conventional methods. Therefore, instead of getting rid of mycotoxins contaminated with food, it is the right action to control the products and prevent mold growth during the production, harvesting, storage and processing stages. It is necessary to monitor the presence of mycotoxin in all these production processes. This is only possible with reliable, precise and quality laboratories and analysis methods.

In the laboratories, multiple mycotoxin analyzes are performed to search for the above mycotoxins. One of the methods used in this analysis is LC-MS / MS. Liquid chromatography - mass - mass spectrometer is a chemical analytical method that combines the mass analysis capabilities of the mass spectrometer with the physical separation properties of liquid chromatography.

The LC-MS / MS method provides reliable results even at very low concentrations, as it can break down ions and consequently utilize multiple reaction monitoring techniques. In addition, this method has high sensitivity and accuracy, has a wide analytical measuring range, requires a small amount of reagent, can be performed multiple measurements simultaneously and is cost-effective.

Within the scope of mycotoxin analysis in advanced laboratories, multiple mycotoxin analysis studies are performed by LC-MS / MS method. These analyzes are based on standards published by domestic and foreign organizations.