Vegetable Products compositions Single or a Mixture In case of situated Aktif pharmaceutical components determination (LC-MS / MS)

Determination of Active Pharmaceutical Ingredients in Single or Mixed Herbal Product Compositions (LC-MS / MS)
Determination of Active Pharmaceutical Ingredients in Single or Mixed Herbal Product Compositions (LC-MS / MS)

Herbal products contain a large number of chemicals and are available in a wide variety of structures. There are a large number of active compounds in plants that will interact with conventional drugs, and unexpected side effects arise in the interaction of these compounds with the drug. Therefore, whatever herbal products are named, regardless of whether they are shown in the food support class in the face of legal regulations, it is necessary to consider these herbal compositions as medicines.

Herbal remedies produced following the standard methods can only have a therapeutic effect if used in appropriate doses and at the right time. Herbal products can be beneficial to human health if used consciously. For the protection of public health, herbal products must be licensed, quality safety and effectiveness should be inspected by the authorities and sold only in pharmacies.

According to the definition adopted by the World Health Organization, herbal medicinal products are medicinal products whose active ingredients are herbal compositions, produced in a suitable pharmaceutical form and prepared in a certain dose. Although the definitions of herbal medicine and herbal medicinal products seem different, they actually have the same meaning.

In the laboratories, active pharmaceutical components are determined in single or mixed form in herbal product compositions within the scope of chemical tests. During these studies, LC-MS / MS method is used besides Q-TOF / MS method. Liquid Chromatography - Mass - Mass Spectrometer (LC-MS / MS) was developed for qualitative residue analysis applications. It gives high speed and accuracy results. From small pharmaceutical compounds to the detection of large proteins, this device is used in food pesticide analysis, determination of residues and impurities in water, analysis of drug metabolites, and many other compounds.

At the same time, the standards adopted by local and foreign organizations are taken as basis during the studies.