Nine species of paralytic shellfish poison (PSP), known as paralyzed shellfish toxins, are known. These are gonyatoxin 1, gonyatoxin 2, gonyatoxin 3, gonyatoxin 4, gonyatoxin 5, gonyatoxin 6, gonyatoxin 7, saxitoxin and neosaxitoxin.

These toxins do not harm the infected fish and shellfish. It only accumulates in the bodies of these creatures. The main poisoning effects are seen in people who consume these products. In other words, shellfish carry poisoning microorganisms that produce these toxins in their bodies. Paralytic Shellfish Poison (PSP) group of toxins, protogonyalax species are produced by dinoflagellata. These paralyzed shellfish toxins, including neosaxitoxin (NEO) toxin, affect people's nervous and muscular systems. Although the most toxic of this group is not as dangerous as goniatoxin 3, neosaxitoxin also poses a risk to human health.

Aquaculture has always been important in terms of meeting the nutritional needs of humans and animals on earth. Of these, molluscs such as oysters, mussels and clams have also been consumed as food sources from the first humans. The increase in the number of poisoning in recent years is due to the increase in the number of dinoflagellata, one of the single-celled marine algae, and the amount of poisons they secrete.

Firstly, poisoning related to the consumption of mussels in 1920 years was noticed in America and the relationship between a certain species of dinoflagellata and poisonous crustaceans was revealed. In fact, crustaceans are not toxic. Toxins that accumulate in their bodies are responsible for shell poisoning.

Paralytic Shellfish Poison Group (PSP) intoxication analyzes are performed by liquid chromatography - mass - mass spectrometry (LC-MS / MS) method within the framework of biotoxin analysis in advanced laboratories. Neosaxitoxin within the scope of these analyzes (NEO-c) to determine the amount of studies are also made. During these studies, standards and test methods published by local and foreign organizations are taken as basis.