The first toxin chemically identified among the toxins that cause poisoning of the shellfish is ocadaic acid. This type of poisoning is mostly caused by shellfish such as mussels and clams. To date, no deaths have been reported in humans, but it is known that ocadaic acid acts as a stimulant for certain tumor activities and causes persistent liver and kidney disorders.

The Regulation on Special Hygiene for Animal Foods issued by the Ministry of Food, Agriculture and Livestock describes the specific hygiene conditions that food enterprises producing animal food must comply with in addition to the principles laid down in the Food Hygiene Regulation. In this regulation, which is prepared on the basis of the Directive on the Specific Hygiene Rules of Animal Foods published in the European Union countries, the total amount of marine biotoxins measured in the bodies or edible parts of live bivalve mollusks shall be as follows:

• For the sum of ocadaic acid, dinophysis and pecteno toxins, 160 okg / kg as the equivalent of ocadaic acid
• 1 mg / kg equivalent of yesso toxins for yesso toxins
• 160 azg / kg as azaspiric acid equivalent for azaspiric acids

In advanced laboratories, azaspiric acid 1 (AZA-1) analysis is performed among Diarrhetic Shellfish Poison Group (DSP) intoxication analyzes by applying LC-MS / MS method within the scope of biotoxin analysis. This method, called liquid chromatography - mass - mass spectrometer, is a chemical analytical method that combines the mass analysis capabilities of the mass spectrometer with the physical separation properties of liquid chromatography. Moreover, this method gives reliable results even at very low concentrations and has high sensitivity and sensitivity.

These analyzes are based on standards and test methods published by domestic and foreign organizations.